Customization: | Available |
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CAS No.: | 1400-61-9 |
Formula: | C47h75no17 |
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Factory Supply Antifungal Antibiotic Raw Material Nystatin Powder
Product Name Nystatin
CAS 1400-61-9
Appearance Light yellow powder
MF C47H75NO17
Molecular Weight 926.095
Purity 99%
Storage Keep in a cool, dry,
Nystatin is a polyene type antibiotic. The first anti-fungal antibiotic was discovered in 1950 when the soil microorganism Streptomyces noursei was found to secrete an anti-fungal substance.Nystatin has conjugated polyene macrolide structure and can inhibit the activity of fungi and erythrum, but has no inhibitory effect on bacteria.
Function
1). Nystatin is often used as prophylaxis in patients who are at risk for fungal infections.
2). It is prescribed in units, with doses varying from 100,000 (for oral infections) to 1 million (for intestinal ones). As it is not absorbed from the
gut, it is safe for oral use and does not have problems of drug interactions.
3). It is also used in cellular biology as an inhibitor of the lipid raft-caveolae endocytosis pathway on mammalian cells, at concentrations around 3 µg/mL.
4). In certain cases, nystatin has been used to prevent the spread of mold on objects such as works of art. For example, it was applied to wood
panel paintings damaged as a result of the Arno River Flood of 1966 in Florence, Italy.
5). Nystatin is also used as a tool by scientists performing "perforated" patch-clamp electrophysiologic recordings of cells. When loaded in the recording pipette, it allows for measurement of electrical currents without washing out the intracellular contents, because it forms pores in the cell membrane that are permeable to only monovalent ions.
Appliction
1. Nystatin is often used as prophylaxis in patients who are at risk for fungal infections, such as AIDS patients with a low CD4+ count and patients receiving chemotherapy.
2. It is prescribed in units, with doses varying from 100,000 (for oral infections) to 1 million (for intestinal ones). As it is not absorbed from the gut, it is safe for oral use and does not have problems of drug interactions.
3. It is also used in cellular biology as an inhibitor of the lipid raft-caveolae endocytosis pathway on mammalian cells, at concentrations around 3 µg/mL.
4. In certain cases, nystatin has been used to prevent the spread of mold on objects such as works of art. For example, it was applied to wood panel paintings damaged as a result of the Arno River Flood of 1966 in Florence, Italy.
Product Name | Nystatin | Molecular Formula | C47h75no17 |
CAS | 1400-61-9 | Shelf Life | 2 Years |
ITEM | Specification | Results |
Appearance | Yellow brown powder | Conforms |
Assay | ≥99% | 99.35% |
Identification | IR:IR spectrum of sample is the same as working standard HPLC:HPLC RT of the sample is the same as the working standard |
Conforms Conforms |
Melting point | 165.0°C~169.0°C | 165.8°C~167.0°C |
Optical rotation | -23°~-29° | -27.4° |
Loss on drying | ≤1.0% | 0.15% |
Residue on Ignition | ≤0.1% | 0.03% |
Heavy Metal | ≤20ppm | Conforms |
Related substances Impurity A Impurity B Impurity C Single impurity Total impurity |
<0.1% <0.1% <0.1% <0.2% <1.0% |
Not detected Not detected 0.02% 0.17% 0.60% |
Comany Information
HOTA wants to help its clients to feel that they have control over their own health. That is why, as a passionate company, we have supplied professional food supplements and plant extracts.
As yet, many people remain unaware that so much can be achieved through food, exercise and supplementation. And that is a missed opportunity, both for the individual and for society. That is why we ensure that our expert knowledge is widely accessible. We actively look for increased knowledge and we substantiate everything that we say, do and produce with scientific research.
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