| Customization: | Available |
|---|---|
| Certification: | ISO, FDA |
| Assay Method: | HPLC, UV |
|
Still deciding? Get samples of US$ 450/kg
Request Sample
|
Suppliers with verified business licenses
Audited Supplier Audited by an independent third-party inspection agency
High Quality Artemisia Annua Extract 99% Artemether Powder CAS 71963-77-4
Prodcut name:Artemether
Synonyms:methyl-dihydroartemisinine,dihydroartemisininmethylether.Decahydro-10-Methoxy-3,6,9-triMethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin
MOQ:1KG
CAS :71963-77-4
Appearance:White powder
Molecular Formula:C16H26O5
Molecular Weight:403.31
Assay:99%
Application:Pharma grade
Packing:As per your request
Storage:Preserve in tight, light-resistant containers in a cool place
Custom synthesis:Available
Artemisinin also known as Qinghaosu (Chinese), and its derivatives are a group of drugs that possess the most rapid action of all current drugs against Plasmodium falciparum malaria.Treatments containing an artemisinin derivative (artemisinin-combination therapies, ACTs) are now standard treatment worldwide for P. falciparum malaria. The starting compound artemisinin is isolated from the plant Artemisia annua, sweet wormwood, an herb employed in Chinese traditional medicine.
Chemically, artemisinin is a sesquiterpene lactone containing an unusual peroxide bridge. This peroxide is believed to be responsible for the drug's mechanism of action.
Use of the drug by itself as a monotherapy is explicitly discouraged by the World Health Organization, as there have been signs that malarial parasites are developing resistance to the drug. Therapies that combine artemisinin with some other antimalarial drug are the preferred treatment for malaria and are both effective and well tolerated in patients. The drug is also increasingly being used in Plasmodium vivax malaria,[3] as well as being a topic of research in cancer treatment.
Function
1.Artemether is an antimalarial agent. It is a water-soluble hemisuccinate derivative of dihydroartemisinin.
2.Artemether is a sesquiterpene lactone isolated from Artemisia annua, a herb that has traditionally been used in China for the treatment of malaria.
3.Artemether and its active metabolite dihydroartemisinin are potent blood schizonticides, active against the ring stage of the parasite.
4.Artemether is ideal for the treatment of severe malaria, including cerebral malaria. It is also active against chloroquine and mefloquine resistant strains of P. falciparum.
5.Artemether is unstable in neutral solution and is therefore only available for injections as artesunic acid.
Application
Cancer treatment
Artemisinin is undergoing early research and testing for the treatment of cancer.Chinese scientists have shown artemisinin has significant anticancer effects against human hepatoma cells.Artemisinin has a peroxide lactone group in its structure, and it is thought that when the peroxide comes into contact with high iron concentrations (common in cancerous cells), the molecule becomes unstable and releases reactive oxygen species. It has been shown to reduce angiogenesis and the expression of vascular endothelial growth factor in some tissue cultures. Recent pharmacological evidence demonstrates the artemisinin-derivative dihydroartemisinin targets human metastatic melanoma cells with induction of NOXA (phorbol-12-myristate-13-acetate-induced protein 1)-dependent mitochondrial apoptosis that occurs downstream of iron-dependent generation of cytotoxic oxidative stress.
Helminth parasites
Serendipitous discovery was made in China while searching for novel anthelmintics for schistosomiasis. Artemisinin and its derivatives are all potent anthelmintics.Artemisinins were later found to possess a broad spectrum of activity against a wide range of trematodes, including Schistosoma japonicum, S. mansoni, S. haematobium, Clonorchis sinensis, Fasciola hepatica and Opisthorchis viverrini. Clinical trials were also successfully conducted in Africa among patients with schistosomiasis.
Comany Information
HOTA wants to help its clients to feel that they have control over their own health. That is why, as a passionate company, we have supplied professional food supplements and plant extracts.
As yet, many people remain unaware that so much can be achieved through food, exercise and supplementation. And that is a missed opportunity, both for the individual and for society. That is why we ensure that our expert knowledge is widely accessible. We actively look for increased knowledge and we substantiate everything that we say, do and produce with scientific research.
We see a future with a better quality of life for everyone: Living Quality. Everything that we strive for has just one single goal: to give you better control of health.
HOTA is dedicated to ensuring every one of our customers enjoys the best in service and product quality. If you have any questions or concerns, our team is always available to help you out!
More Advantages:
1. Leading factory price
2. Huge range of product in stock
3. Research & Development
Our R&D team is continuously developing new product to meet the market.
4. Quality control
At HOTA Co., Ltd, this process is probably the most stringent of all. To us, quality is a commitment. It is a constant process and a continuous improvement.
5. OEM Service: Capsules or Tablets available
Safe, Secure Packaging - Full sealed
1-25kgs: Aluminium bag outside and double plastic bags inside
More than 25kgs: Fiber drum outside and plastic bags inside
Fast, Secure Shipping
|
By Express |
By air |
By sea |
|
Suitable for under 25kg |
Suitable for more than 25kg |
Suitable for more than 500kg |
Q1: When will my order be shipped?
A: Within 3 working days after the payment.
Q2: Can i get some samples?
A: Yes, contact me to know more about sample
Q3: How to confirm the Product Quality before placing orders?
A: Every product is with professional COA. Please be sure about the quality.
If any doubt, sample is available to you to be tested before large quantity order.
Q4: How to start orders or make payments?
A: Payment by T/T, Western Union,MoneyGram etc .
){kind=link}